Cho often uses his childhood experiences as an Asian American in the South in his comedy. "I'm an Asian with a Southern accent," remarks Cho, "To a lot of people, that right there is funny."
Henry Cho recently earned his nickname, "Mr. Clean" for his always-clean comedy.
He has appeared in three feature films. First, starring opposite Tom Arnold and David Alan Grier in McHale's Navy. In 2001, he appeared in the Farrelly Brothers' movie Say It Isn't So with Heather Graham and Chris Klein. Most recently, in 2006, he appeared in Material Girls starring Hilary and Haylie Duff.
He has had his own Comedy Central special entitled "Henry Cho: What's That Clickin' Noise?"
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